Randomized, double‐blind study of pramipexole with placebo and bromocriptine in advanced Parkinson's disease
Identifieur interne : 003F71 ( Main/Exploration ); précédent : 003F70; suivant : 003F72Randomized, double‐blind study of pramipexole with placebo and bromocriptine in advanced Parkinson's disease
Auteurs : Yoshikuni Mizuno [Japon] ; Nobuo Yanagisawa [Japon] ; Sadako Kuno [Japon] ; Mitsutoshi Yamamoto [Japon] ; Kazuko Hasegawa [Japon] ; Hideki Origasa [Japon] ; Hisayuki Kowa [Japon]Source :
- Movement Disorders [ 0885-3185 ] ; 2003-10.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Adulte.
English descriptors
- KwdEn :
- Activities of Daily Living, Adjuvant treatment, Adult, Advanced stage, Aged, Antiparkinson Agents (therapeutic use), Benzothiazoles, Bromocriptine, Bromocriptine (therapeutic use), Chemotherapy, Comparative study, Demography, Dose-Response Relationship, Drug, Double blind study, Double-Blind Method, Drug Administration Schedule, Drug Tolerance, Female, Humans, Levodopa, Male, Middle Aged, Multicenter study, Parkinson Disease (drug therapy), Parkinson disease, Parkinson's disease, Pramipexole, Prognosis, Prospective Studies, Quality of Life, Randomization, Thiazoles (therapeutic use), Time Factors, Treatment Outcome, bromocriptine, drug comparison, levodopa, pramipexole, randomized controlled trial (RCT).
- MESH :
- chemical , therapeutic use : Antiparkinson Agents, Bromocriptine, Thiazoles.
- drug therapy : Parkinson Disease.
- Activities of Daily Living, Aged, Benzothiazoles, Demography, Dose-Response Relationship, Drug, Double-Blind Method, Drug Administration Schedule, Drug Tolerance, Female, Humans, Male, Middle Aged, Prospective Studies, Quality of Life, Time Factors, Treatment Outcome.
Abstract
We compared the efficacy and safety of pramipexole (PPX) with placebo in the treatment of advanced Parkinson's disease (PD) as an adjunct to levodopa. A bromocriptine (BR) group was included to enable determination of the noninferiority of PPX relative to BR as the standard treatment. © 2003 Movement Disorder Society
Url:
DOI: 10.1002/mds.10508
Affiliations:
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Le document en format XML
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<series><title level="j">Movement Disorders</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Activities of Daily Living</term>
<term>Adjuvant treatment</term>
<term>Adult</term>
<term>Advanced stage</term>
<term>Aged</term>
<term>Antiparkinson Agents (therapeutic use)</term>
<term>Benzothiazoles</term>
<term>Bromocriptine</term>
<term>Bromocriptine (therapeutic use)</term>
<term>Chemotherapy</term>
<term>Comparative study</term>
<term>Demography</term>
<term>Dose-Response Relationship, Drug</term>
<term>Double blind study</term>
<term>Double-Blind Method</term>
<term>Drug Administration Schedule</term>
<term>Drug Tolerance</term>
<term>Female</term>
<term>Humans</term>
<term>Levodopa</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Multicenter study</term>
<term>Parkinson Disease (drug therapy)</term>
<term>Parkinson disease</term>
<term>Parkinson's disease</term>
<term>Pramipexole</term>
<term>Prognosis</term>
<term>Prospective Studies</term>
<term>Quality of Life</term>
<term>Randomization</term>
<term>Thiazoles (therapeutic use)</term>
<term>Time Factors</term>
<term>Treatment Outcome</term>
<term>bromocriptine</term>
<term>drug comparison</term>
<term>levodopa</term>
<term>pramipexole</term>
<term>randomized controlled trial (RCT)</term>
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<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiparkinson Agents</term>
<term>Bromocriptine</term>
<term>Thiazoles</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Activities of Daily Living</term>
<term>Aged</term>
<term>Benzothiazoles</term>
<term>Demography</term>
<term>Dose-Response Relationship, Drug</term>
<term>Double-Blind Method</term>
<term>Drug Administration Schedule</term>
<term>Drug Tolerance</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Prospective Studies</term>
<term>Quality of Life</term>
<term>Time Factors</term>
<term>Treatment Outcome</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Adulte</term>
<term>Bromocriptine</term>
<term>Chimiothérapie</term>
<term>Etude comparative</term>
<term>Etude double insu</term>
<term>Etude multicentrique</term>
<term>Lévodopa</term>
<term>Parkinson maladie</term>
<term>Pramipexole</term>
<term>Pronostic</term>
<term>Randomisation</term>
<term>Stade avancé</term>
<term>Traitement adjuvant</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Adulte</term>
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<front><div type="abstract" xml:lang="en">We compared the efficacy and safety of pramipexole (PPX) with placebo in the treatment of advanced Parkinson's disease (PD) as an adjunct to levodopa. A bromocriptine (BR) group was included to enable determination of the noninferiority of PPX relative to BR as the standard treatment. © 2003 Movement Disorder Society</div>
</front>
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<tree><country name="Japon"><noRegion><name sortKey="Mizuno, Yoshikuni" sort="Mizuno, Yoshikuni" uniqKey="Mizuno Y" first="Yoshikuni" last="Mizuno">Yoshikuni Mizuno</name>
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<name sortKey="Hasegawa, Kazuko" sort="Hasegawa, Kazuko" uniqKey="Hasegawa K" first="Kazuko" last="Hasegawa">Kazuko Hasegawa</name>
<name sortKey="Kowa, Hisayuki" sort="Kowa, Hisayuki" uniqKey="Kowa H" first="Hisayuki" last="Kowa">Hisayuki Kowa</name>
<name sortKey="Kuno, Sadako" sort="Kuno, Sadako" uniqKey="Kuno S" first="Sadako" last="Kuno">Sadako Kuno</name>
<name sortKey="Origasa, Hideki" sort="Origasa, Hideki" uniqKey="Origasa H" first="Hideki" last="Origasa">Hideki Origasa</name>
<name sortKey="Yamamoto, Mitsutoshi" sort="Yamamoto, Mitsutoshi" uniqKey="Yamamoto M" first="Mitsutoshi" last="Yamamoto">Mitsutoshi Yamamoto</name>
<name sortKey="Yanagisawa, Nobuo" sort="Yanagisawa, Nobuo" uniqKey="Yanagisawa N" first="Nobuo" last="Yanagisawa">Nobuo Yanagisawa</name>
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